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Darvocet, Darvon & Tylenol: Prescription Drug Abuse & Testing

Dextropropoxyphenes:

These are the mild analgesic agents of the opioid category which are frequently used to treat mild to moderate pain. These are also used as antitussive i.e. a medicine used to suppress or relieve coughing.

Use & Abuse:

Dextropropoxyphene, like codeine, is a weak opioid. However, approximately 10-20% of the Caucasian population is unable to metabolize codeine, so dextropropoxyphene is particularly useful with such people. In pure form, dextropropoxyphene is commonly used to ease the withdrawal symptoms in people addicted to opioids. Being very weak in comparison to the opioids that are commonly abused, dextropropoxyphene can only act as a “partial” substitute. It does not have much effect on mental cravings; however it can be effective in alleviating physical withdrawal effects, such as muscle cramps.

Dextropropoxyphene has been a subject to some controversy. While many physicians prescribe it for a wide range of mildly to moderately painful symptoms as well as for treatment of diarrhea, many others refuse to prescribe it, citing its highly addictive nature and limited effectiveness.

Tylenol:

It is a popular American brand of drugs for relieving pain, reducing fever, and relieving the symptoms of allergies, cold, cough, and the flu. The active ingredient of its original, flagship product, acetaminophen (called “paracetamol” outside North America), is marketed for headaches, fever, muscle and body pain, arthritis, and joint pain. Like the words “acetaminophen” and “paracetamol”, the brand name is derived from the chemical name for the compound, N-acetyl-para-aminophenol (APAP). It is available over the counter without prescription, has few side effects, and reacts with very few medications. Acetaminophen is also found in other narcotic based analgesics such as Percocet which contains oxycodone. However, some classes of stronger pain relievers also contain codeine.

Darvon:

Darvon is a pure dextropropoxyphene preparation available in the U.S. that does not contain acetaminophen (Tylenol). It was made by Eli Lilly. It came under heavy fire in 1978 by consumer groups which said that Darvon was associated with suicide. Darvon was never withdrawn from the market, but Lilly has waged a sweeping, and largely successful, campaign among doctors, pharmacists and Darvon users to defend the drug as safe when it is used in proper doses and not mixed with alcohol.

Darvocet:

In the United States, dextropropoxyphene hydrochloric acid is available as a prescription formulation with acetaminophen (Tylenol) in ratio anywhere from 30mg / 600mg to 100mg / 650mg, respectively. These are usually named as Darvocet.

Dextropropoxyphene/Acetaminophen Testing:

A diverse array of techniques is available to test for drug abuse and Dextropropoxyphenes and/or acetaminophen containing compounds are no exception. As shown in the figure below, some amount of acetaminophen remains unchanged while rest of it forms different metabolites. Same is true for Dextropropoxyphenes and derivative compounds like Darvon.

Tylenols & Darvocets can be detected by acetaminophen specific methods while Darvons can be detected by Dextropropoxyphene specific methods, be it urine or hair drug testing based, GC/MS based diagnostic techniques or Antibody based kits.

These unchanged Dextropropoxyphenes & acetaminophen compounds and their metabolized products can be detected using any of the following methods:

•Urine based Dextropropoxyphene/acetaminophen/metabolite testing

•Hair follicle based Dextropropoxyphene/acetaminophen/metabolite detection

•GC based Dextropropoxyphene/acetaminophen/metabolite detection

•Mass spec based Dextropropoxyphene/acetaminophen/metabolite testing

•Dextropropoxyphene / acetaminophen / metabolite-specific antibody based diagnostic kits

About the Author

This Article is written by Tarun Gupta, the author of TestCountry Health Information Resources, a longer version of this article is located at Darvocet, Darvon & Tylenol, and resources from other home health and wellness testing sources are used such as TestCountry Substance Abuse Testing.

what is a substance abuse drug test and how far back does it show ” how many days”?

Well there are more than one type of drug test. Most labs or even probation offices, Treatment Centers use a self reading urine cup. That gives a quick answer right then. If the answer is positive, the testee is given the option of admitting to use, or denying. If the testee denies, then the test is sent into the lab for confirmation. Most tests check for Alcohol, THC (active ingredient in Marijuana), Amphetamines, Opiates, Cocaine, PCP (angel dust), Benzodiazepines (Valium, Xanax, Klonopin, etc). There are other drugs that can be tested for, and some tests break down the Opiates and Amphetamines into types.

As for how far back it shows positive, that depends on the drug. Alcohol dissipates at the rate of one ounce per hour. So that is out quickly. However, there is a new “80 hour” test that can be run on alcohol and it shows positive for 80 hours after drinking. That test is getting alot of folks caught because they are used to being able to drink at night and be clean by morning.

Marijuana stores in fat cells. This has nothing to do with the size of the testee. It has everything to do with how much and how often one smokes Marijuana. Fat people don’t have more fat cells than skinny people, they just have ‘fluffier’ fat cells. There is one difference between the sexes, girls have more fat cells than boys do –because girls were made to have babies. Sometimes girls who smoke alot of pot will stay dirty longer. So anyway, if one smokes alot of pot and smokes daily, they could conceivably stay dirty for up to 30 to 60 days or so. If someone usually doesn’t smoke pot at all but took a hit off a joint and tests a few days later, chances are they will be clean as a whistle.

As for the rest of the drugs……. You can usually count on being positive on a drug screen for about three to four days. They are almost always out of the system by then.

There are some agencies that use hair follicles for testing, and they can test back for about 3 to 4 months with hair follicles. They can use any hair, the length of the hair doesn’t matter. Mostly Child Protection uses hair follicle testing.

Good luck. Honestly the best thing to do is stay clean and learn to deal with life. <3

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